The Prince Charles Hospital - Cardiology Clinical Research Centre

-27.388547 - 153.02271

No

2 weeks

Cardiology Clinical Research Centre (CCRC): Leading the Way in Groundbreaking Cardiac Research and Innovation
At the heart of the Cardiology Department at The Prince Charles Hospital (TPCH), the Cardiology Clinical Research Centre (CCRC) stands as a beacon of excellence in the global medical research community. As the premier hub for clinical trials and pioneering research, we are dedicated to advancing cardiac care by driving the rapid evolution of life-saving therapies, technologies, and first-in-human device trials. Our collaborative team of world-class cardiac researchers, clinicians, interventionalists and clinical research coordinators is committed to improving the quality of life and extending the longevity of cardiac patients worldwide.

World-Class Innovation in Cardiology
CCRC continues to be one of the largest and most influential cardiology research centres in Australia, renowned for its expertise in conducting international multi-centre clinical trials. We are also proud to lead the charge in clinical research and investigator-initiated research that pushes the boundaries of modern cardiology. Our work directly contributes to the global knowledge base, ensuring that patients everywhere benefit from the latest breakthroughs in cardiac care.

CCRC: Pioneering the Future of Cardiac Research and Transforming Patient Care
At the Cardiology Clinical Research Centre (CCRC), we are committed to advancing the frontiers of cardiology through innovative research and transformative therapies that redefine patient care. Our focus spans across six critical areas, each dedicated to driving breakthrough advancements in cardiac medicine and improving the lives of patients worldwide. With our expertise, we are not only contributing to the global body of knowledge, but also leading the way in clinical trials that pave the path for new standards of care.


Services and Specilaities:

1. Interventional Cardiology: Advancing Cutting-Edge Therapies
Our world-renowned interventional cardiology program is at the forefront of revolutionary treatments, focusing on first-in-human clinical trials for procedures such as Transcatheter Aortic Valve Implantation (TAVI), Transcatheter Mitral Valve, Tricuspid Clip and Valve, and Mitral Clip Implantation, InterAtrial Shunt Device, and Percutaneous Coronary Intervention Stents and Balloons. These groundbreaking trials have already led to the approval of several devices by the FDA and TGA, changing the landscape of cardiac care and setting new standards for patient outcomes.
2. Heart Failure: Transforming Treatment with Innovative Therapies
The CCRC heart failure research program is dedicated to improving the quality of life for patients battling heart failure. Our focus includes new therapies, interventional procedures, and home monitoring devices that extend and enhance life for heart failure patients—across diagnosis, treatment, and ongoing care.
3. Infective Endocarditis: Pioneering Research for Future Discoveries
Our Infective Endocarditis Registry and Biobank, the first of its kind in Australia, is opening doors to new scientific discoveries that will change the way we understand and treat this complex condition. This innovative resource is set to revolutionize the field and propel future advancements in infective endocarditis care.
4. Hyperlipidemia and Cardiovascular Disease: Reducing Risk, Improving Outcomes
We are leading clinical trials on novel lipid-lowering therapies to reduce the risk of cardiovascular disease and prevent rehospitalization, heart attacks, strokes, and mortality. Our research aims to make significant strides in the prevention and management of hyperlipidemia and its related cardiovascular conditions.
5. Electrophysiology: Innovating Heart Rhythm Treatments
Our electrophysiologists are at the cutting edge of understanding heart rhythm disturbances, working to develop new treatments, including first-in-human device trials. In collaboration with international clinical trial sponsors, the research being undertaken aims to provide patients with more effective solutions for managing arrhythmias and improving heart health.
6. Echocardiography: A World-Leading Comparative Study
The CATHARSIS Program represents the world’s largest and most comprehensive echocardiography comparative study, advancing the diagnostic capabilities of echocardiography and providing invaluable insights into cardiac health.

At CCRC, we are not only shaping the future of cardiology, we are transforming it. Our state-of-the-art research drives clinical advancements that benefit patients across the globe.

CCRC: Pioneering the Future of Cardiology and Heart Failure Research
At the Cardiology Clinical Research Centre (CCRC), we are at the forefront of groundbreaking advancements in cardiology, leading the charge in the coordination of novel, cutting-edge, and first-in-human interventional and structural percutaneous device clinical trials. As one of the largest Heart Failure research centres in Australia, CCRC is dedicated to transforming the future of cardiac care and improving patient outcomes on a global scale.

A Hub for Innovation and Collaboration
CCRC is more than just a research centre—it’s a thriving ecosystem of expertise, collaboration, and opportunity. We provide a platform that not only supports seasoned, experienced researchers, but also nurtures aspiring and novice researchers, higher-degree students, and postgraduate students. We are committed to fostering the next generation of leaders in cardiology research, offering invaluable hands-on experience and mentorship to those eager to contribute to the future of medical science.
Join Us in Shaping the Future
As we continue to push the boundaries of cardiac research, we invite researchers, collaborators, and donors to join us on our mission to advance the field of cardiology. Together, we can continue to lead the way in pioneering therapies, technologies, and treatments that will revolutionize patient care and improve lives worldwide.

- HREC Committee Name: Metro North HREC
- Meeting frequency: Monthly
- Types of HREC (IRB/ERB/ETHICS) Committee that are used: Central Acting as Local
- Mandate distribution of safety: Yes

- Handling Investigational Product: Yes
- Training program for the research staff: Yes
- Include GCP: Yes
- Facility written sop during transportation to satellite site: Yes

- Required Licenses or Registrations: Yes
- Does the Facility have the ability to handle radio-labelled Investigational Products? Yes

- Investigational Product: Horizontal laminar flow hood (non-hazardous drug preparation) available in June 2025
- Centrifuge: Yes
- Refrigerated Centrifuge: Yes

- Record Archiving: Yes
- EMR/EHR systems: In-house system
- Has your Clinical Trial Site or Service been accredited? Yes
- Audit Type: Other

- Refrigerator (2 to 8 Degrees C): Yes
- Freezer (-20 to -30 Degrees C): Yes
- Investigational Freezer (-70 to -80 Degrees C): Yes
- Investigational Freezer (Liquid Nitrogen -135 Degrees C): Yes
- Does this equipment have back-up power? Yes
- Does this equipment provide Min/Max Temperature Monitoring? Yes
- Do you have the ability to generate a temperature monitoring log for this equipment? Yes
- Does this equipment have a temperature alarm? Yes
- Do you have an SOP which supports calibration of this equipment? Yes